CONCLUSIONS: If patients have poor integrity of the circle of Willis, the risk of recurrent stroke may be increased. Variations of circle of Willis in human cadavers. The circle of Willis also allows blood to flow across the midline of the brain if an artery on one side is occluded. Shubhangi Y. The circle of Willis score of the patients with complete arterial occlusion was 1.33±1.52 in the fatal stroke group (n=3) and 3.20±1.64 in the asymptomatic group (n=6, p=0.099). It is named after Thomas Willis, an English physician. The circle of Willis is a continuous loop of arteries in the brain that provides collateral circulation. Int J Anat Var. When you turn your head from side-to-side or up and down, the arteries in your neck stretch and flex. It has a safety valve function in the brain. This surgery involves ligating the left common carotid artery and a complete Circle of Willis is critical to enable the right carotid artery to provide the blood supply to the entire brain. ABSTRACT Aims and Objective: The blood supply of brain is of great importance because of the metabolic demands of the nervous tissue. 2018;11(2): 43-45. In the process, they may become compressed, which restricts blood flow. The absence of some CoW elements may be fatal for patients with internal carotid artery stenosis39. When performing the HD-X or HD-XG surgery in mice, it is important that the animal strain has a complete Circle of Willis. Willis describes a number of cases that demonstrate the function of the arterial circle in providing compensatory collateral blood flow (Vrselja, Brkic, Mrdenovic, Radic, & Curic, 2014). The circle of Willis (CW) was first described 400 years ago by Thomas Willis as an important vascular ring at the base of the brain (Vrselja, Brkic, Mrdenovic, Radic, & Curic, 2014). The anastomosis between the right and left ICAs and the vertebrobasilar circulation by means of communicating arteries form this ringlike structure. This network of arteries provides blood to be distributed to both hemispheres from the internal carotid arteries or vertebral arteries. The circle of Willis encircles the stalk of the pituitary gland and provides important communications between the blood supply of the forebrain and hindbrain (ie, between the internal carotid and vertebro-basilar systems following obliteration of primitive embryonic connections). The Circle of Willis is a network of blood vessels that connects the two hemispheres. The circle of Willis (also called Willis' Circle, Loop of Willis, cerebral arterial circle, and Willis Polygon) is a circle of arteries at the base of brain that supply blood to the brain and surrounding structures. 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